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Rhythmic SAF-A Binding Underlies Circadian Transcription of the Bmal1 Gene

Although Bmal1 is a key component of the mammalian clock system, little is understood about the actual mechanism of circadian Bmal1 gene transcription, particularly at the chromatin level. Here we discovered a unique chromatin structure within the Bmal1 promoter. The RORE region, which is a critical...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Onishi, Yoshiaki, Hanai, Syuji, Ohno, Tomoya, Hara, Yasuhiro, Ishida, Norio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423175/
https://ncbi.nlm.nih.gov/pubmed/18332112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02227-07
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