CD4(+) T help promotes influenza virus-specific CD8(+) T cell memory by limiting metabolic dysfunction

There is continued interest in developing novel vaccine strategies that induce establish optimal CD8(+) cytotoxic T lymphocyte (CTL) memory for pathogens like the influenza A viruses (IAVs), where the recall of IAV-specific T cell immunity is able to protect against serologically distinct IAV infect...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cullen, Jolie G., McQuilten, Hayley A., Quinn, Kylie M., Olshansky, Moshe, Russ, Brendan E., Morey, Alison, Wei, Sanna, Prier, Julia E., La Gruta, Nicole L., Doherty, Peter C., Turner, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410826/
https://ncbi.nlm.nih.gov/pubmed/30787194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808849116
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