Extrinsically derived TNF is primarily responsible for limiting antiviral CD8+ T cell response magnitude

TNF is a pro-inflammatory cytokine produced by both lymphoid and non-lymphoid cells. As a consequence of the widespread expression of its receptors (TNFR1 and 2), TNF plays a role in many important biological processes. In the context of influenza A virus (IAV) infection, TNF has variably been impli...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Quinn, Kylie M., Kan, Wan-Ting, Watson, Katherine A., Liddicoat, Brian J., Swan, Natasha G., McQuilten, Hayley, Denton, Alice E., Li, Jasmine, Chen, Weisan, Brown, Lorena E., Jackson, David C., Reading, Patrick C., Doherty, Peter C., Kedzierska, Katherine, Kedzierski, Lukasz, Turner, Stephen J., La Gruta, Nicole L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590991/
https://ncbi.nlm.nih.gov/pubmed/28886201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184732
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