Hypoxia-inducible factors in CD4(+) T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity

T cell help in humoral immunity includes interactions of B cells with activated extrafollicular CD4(+) and follicular T helper (Tfh) cells. Each can promote antibody responses but Tfh cells play critical roles during germinal center (GC) reactions. After restimulation of their antigen receptor (TCR)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Cho, Sung Hoon, Raybuck, Ariel L., Blagih, Julianna, Kemboi, Edna, Haase, Volker H., Jones, Russell G., Boothby, Mark R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2019
Gaiak:
PNAS Plus
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500120/
https://ncbi.nlm.nih.gov/pubmed/30988188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1811702116
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