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Differentiation-dependent functional and epigenetic landscapes for cytokine genes in virus-specific CD8(+) T cells
Although the simultaneous engagement of multiple effector mechanisms is thought to characterize optimal CD8(+) T-cell immunity and facilitate pathogen clearance, the differentiation pathways leading to the acquisition and maintenance of such polyfunctional activity are not well understood. Division-...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174616/ https://ncbi.nlm.nih.gov/pubmed/21876173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112520108 |
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