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Holding All the Cards—How Fanconi Anemia Proteins Deal with Replication Stress and Preserve Genomic Stability

Fanconi anemia (FA) is a hereditary chromosomal instability disorder often displaying congenital abnormalities and characterized by a predisposition to progressive bone marrow failure (BMF) and cancer. Over the last 25 years since the discovery of the first linkage of genetic mutations to FA, its mo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Genes (Basel)
Hauptverfasser: Datta, Arindam, Brosh, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409899/
https://ncbi.nlm.nih.gov/pubmed/30813363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020170
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