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Holding All the CARDs: How MALT1 Controls CARMA/CARD-Dependent Signaling

The scaffold proteins CARMA1-3 (encoded by the genes CARD11, -14 and -10) and CARD9 play major roles in signaling downstream of receptors with immunoreceptor tyrosine activation motifs (ITAMs), G-protein coupled receptors (GPCR) and receptor tyrosine kinases (RTK). These receptors trigger the format...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Juilland, Mélanie, Thome, Margot
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125328/
https://ncbi.nlm.nih.gov/pubmed/30214442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01927
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