A carregar...
The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a
Here we explored the mechanism of R-loop formation and DNA cleavage by type V CRISPR Cas12a (formerly known as Cpf1). We first used a single-molecule magnetic tweezers (MT) assay to show that R-loop formation by Lachnospiraceae bacterium ND2006 Cas12a is significantly enhanced by negative DNA superc...
Na minha lista:
| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409811/ https://ncbi.nlm.nih.gov/pubmed/30813348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020169 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|