Mechanistic insights into the pH-dependent membrane peptide ATRAM

pH-responsive peptides are promising therapeutic molecules that can specifically target the plasma membrane in the acidified extracellular medium that bathes cells in tumors. We designed the acidity-triggered rational membrane (ATRAM) peptide to have a pH-responsive membrane interaction. At physiolo...

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Veröffentlicht in:J Control Release
Hauptverfasser: Nguyen, Vanessa. P., Palanikumar, Loganathan, Kennel, Stephen J., Alves, Daiane S., Ye, Yujie, Wall, Jonathan S., Magzoub, Mazin, Barrera, Francisco N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408977/
https://ncbi.nlm.nih.gov/pubmed/30763623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.02.010
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