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Targeting insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in metastatic melanoma to increase efficacy of BRAF(V600E) inhibitors

Melanoma is one of the deadliest forms of skin cancer. Although BRAF inhibitors significantly enhance survival of metastatic melanoma patients, most patients relapse after less than a year of treatment. We previously reported that mRNA binding protein Insulin-like growth factor 2 mRNA-binding protei...

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發表在:Mol Carcinog
Main Authors: Kim, TaeWon, Havighurst, Thomas, Kim, KyungMann, Albertini, Mark, Xu, Yaohui G., Spiegelman, Vladimir S.
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408214/
https://ncbi.nlm.nih.gov/pubmed/29369405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22786
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