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Protein ensembles: how does nature harness thermodynamic fluctuations for life?: The diverse functional roles of conformational ensembles in the cell

All soluble proteins populate conformational ensembles that together constitute the native state. Their fluctuations in water are intrinsic thermodynamic phenomena, and the distributions of the states on the energy landscape are determined by statistical thermodynamics; however, they are optimized t...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Wei, Guanghong, Xi, Wenhui, Nussinov, Ruth, Ma, Buyong
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407618/
https://ncbi.nlm.nih.gov/pubmed/26807783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.5b00562
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