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The role of dynamic conformational ensembles in biomolecular recognition

Molecular recognition is central to all biological processes. For the past fifty years, Koshland’s ‘induced fit’ hypothesis has been the textbook explanation for molecular recognition events. However, recent experimental evidence supports an alternative mechanism. ‘Conformational selection’ postulat...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Boehr, David D., Nussinov, Ruth, Wright, Peter E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916928/
https://ncbi.nlm.nih.gov/pubmed/19841628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.232
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