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The role of dynamic conformational ensembles in biomolecular recognition
Molecular recognition is central to all biological processes. For the past fifty years, Koshland’s ‘induced fit’ hypothesis has been the textbook explanation for molecular recognition events. However, recent experimental evidence supports an alternative mechanism. ‘Conformational selection’ postulat...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916928/ https://ncbi.nlm.nih.gov/pubmed/19841628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.232 |
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