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Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling
BACKGROUND: Pulmonary hypertension (PH) is a progressive and fatal disease. While cigarette smoke can change DNA methylation status, the role of such molecular alterations in smoke-associated PH is unclear. METHODS: A PH rat model was developed by exposing animals to cigarette smoke for 3 months. Ri...
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| Publicado no: | Respir Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6407244/ https://ncbi.nlm.nih.gov/pubmed/30845941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1014-1 |
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