Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters

BACKGROUND: Cigarette smoking is an important risk factor for pulmonary arterial hypertension (PAH) in chronic obstructive pulmonary disease (COPD). Chymase has been shown to function in the enzymatic production of angiotensin II (AngII) and the activation of transforming growth factor (TGF)-β1 in t...

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Detalhes bibliográficos
Main Authors: Wang, Tao, Han, Su-Xia, Zhang, Shang-Fu, Ning, Yun-Ye, Chen, Lei, Chen, Ya-Juan, He, Guang-Ming, Xu, Dan, An, Jin, Yang, Ting, Zhang, Xiao-Hong, Wen, Fu-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853423/
https://ncbi.nlm.nih.gov/pubmed/20356378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-36
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