Cigarette Smoke Extract Stimulates Rat Pulmonary Artery Smooth Muscle Cell Proliferation via PKC-PDGFB Signaling

Accumulating evidence suggests a direct role for cigarette smoke in pulmonary vascular remodeling, which contributes to the development of pulmonary hypertension. However, the molecular mechanisms underlying this process remain poorly understood. Platelet-derived growth factor (PDGF) is a potential...

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Autors principals: Xing, Ai-ping, Du, Yong-cheng, Hu, Xiao-yun, Xu, Jian-ying, Zhang, Huan-ping, Li, Yi, Nie, Xin
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384980/
https://ncbi.nlm.nih.gov/pubmed/22754279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/534384
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