Defining the Determinants of Specificity of Plasmodium Proteasome Inhibitors

The Plasmodium proteasome is an emerging antimalarial target due to its essential role in all the major life cycle stages of the parasite and its contribution to the establishment of resistance to artemisinin (ART)-based therapies. However, because of a similarly essential role for the host proteaso...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Yoo, Euna, Stokes, Barbara H., de Jong, Hanna, Vanaerschot, Manu, Kumar, TRS, Lawrence, Nina, Njoroge, Mathew, Garcia, Arnold, Van der Westhuyzen, Renier, Momper, Jeremiah D., Ng, Caroline L., Fidock, David A., Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407133/
https://ncbi.nlm.nih.gov/pubmed/30107725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06656
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