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The cryo-EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria

Plasmodium falciparum is the parasite responsible for the most severe form of malaria. Its increasing resistance to existing antimalarials represents a major threat to human health and urges the development of new therapeutic strategies to fight malaria. The proteasome is a protease complex essentia...

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Veröffentlicht in:FEBS J
Hauptverfasser: Li, Hao, Bogyo, Matthew, da Fonseca, Paula C. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140733/
https://ncbi.nlm.nih.gov/pubmed/27286897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13780
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