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Developing Targeted Therapies That Exploit Aberrant Histone Ubiquitination in Cancer
Histone ubiquitination is a critical epigenetic mechanism regulating DNA-driven processes such as gene transcription and DNA damage repair. Importantly, the cellular machinery regulating histone ubiquitination is frequently altered in cancers. Moreover, aberrant histone ubiquitination can drive onco...
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| Publicado no: | Cells |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6406838/ https://ncbi.nlm.nih.gov/pubmed/30781493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8020165 |
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