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Targeting ubiquitination for cancer therapies

Ubiquitination, the structured degradation and turnover of cellular proteins, is regulated by the ubiquitin–proteasome system (UPS). Most proteins that are critical for cellular regulations and functions are targets of the process. Ubiquitination is comprised of a sequence of three enzymatic steps,...

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Bibliografski detalji
Izdano u:Future Med Chem
Glavni autori: Morrow, John Kenneth, Lin, Hui-Kuan, Sun, Shao-Cong, Zhang, Shuxing
Format: Artigo
Jezik:Inglês
Izdano: Future Science Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976843/
https://ncbi.nlm.nih.gov/pubmed/26630263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.148
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