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Targeting ubiquitination for cancer therapies

Ubiquitination, the structured degradation and turnover of cellular proteins, is regulated by the ubiquitin–proteasome system (UPS). Most proteins that are critical for cellular regulations and functions are targets of the process. Ubiquitination is comprised of a sequence of three enzymatic steps,...

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Publicat a:Future Med Chem
Autors principals: Morrow, John Kenneth, Lin, Hui-Kuan, Sun, Shao-Cong, Zhang, Shuxing
Format: Artigo
Idioma:Inglês
Publicat: Future Science Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976843/
https://ncbi.nlm.nih.gov/pubmed/26630263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.148
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