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Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy

BACKGROUND: Cardiac hypertrophy is an adaptive remodeling event that may improve or diminish contractile performance of the heart. Physiologic and pathologic hypertrophy yield distinct outcomes, yet both are dependent on caspase‐directed proteolysis. This suggests that each form of myocardial growth...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Putinski, Charis, Abdul‐Ghani, Mohammad, Brunette, Steve, Burgon, Patrick G., Megeney, Lynn A.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405540/
https://ncbi.nlm.nih.gov/pubmed/30486716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010404
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