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Caspase Cleavage of Gelsolin Is an Inductive Cue for Pathologic Cardiac Hypertrophy

BACKGROUND: Cardiac hypertrophy is an adaptive remodeling event that may improve or diminish contractile performance of the heart. Physiologic and pathologic hypertrophy yield distinct outcomes, yet both are dependent on caspase‐directed proteolysis. This suggests that each form of myocardial growth...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Putinski, Charis, Abdul‐Ghani, Mohammad, Brunette, Steve, Burgon, Patrick G., Megeney, Lynn A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6405540/
https://ncbi.nlm.nih.gov/pubmed/30486716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.010404
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