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Structural basis for KCTD-mediated rapid desensitization of GABA(B) signaling
The GABA(B) receptor is one of the principal inhibitory neurotransmitter receptors in the brain, and it signals through heterotrimeric G proteins to activate a variety of effectors including G protein-coupled inwardly-rectifying potassium channels (GIRKs)(1,2). GABA(B) receptor signaling is tightly...
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| Publicado en: | Nature |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6405316/ https://ncbi.nlm.nih.gov/pubmed/30814734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0990-0 |
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