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Distinctive single-channel properties of α4β2-nicotinic acetylcholine receptor isoforms
Central nervous system nicotinic acetylcholine receptors (nAChR) are predominantly of the α4β2 subtype. Two isoforms exist, with high or low agonist sensitivity (HS-(α4β2)(2)β2- and LS-(α4β2)(2)α4-nAChR). Both isoforms exhibit similar macroscopic potency and efficacy values at low acetylcholine (ACh...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6405073/ https://ncbi.nlm.nih.gov/pubmed/30845161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213143 |
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