Small Molecule Targeting of Specific BAF (mSWI/SNF) complexes for HIV Latency Reversal

The persistence of a pool of latently HIV-1-infected cells despite combination Anti-Retroviral Therapy (cART) treatment is the major roadblock for a cure. The BAF (mammalian SWI/SNF) chromatin remodeling complex is involved in establishing and maintaining viral latency, making it an attractive drug...

Full description

Saved in:
Bibliographic Details
Published in:Cell Chem Biol
Main Authors: Marian, Christine A., Stoszko, Mateusz, Wang, Lili, Leighty, Matthew W., de Crignis, Elisa, Maschinot, Chad A., Gatchalian, Jovylyn, Carter, Benjamin C., Chowdhury, Basudev, Hargreaves, Diana C., Duvall, Jeremy R., Crabtree, Gerald R., Mahmoudi, Tokameh, Dykhuizen, Emily C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404985/
https://ncbi.nlm.nih.gov/pubmed/30197195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.08.004
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items