Small Molecule Targeting of Specific BAF (mSWI/SNF) complexes for HIV Latency Reversal

The persistence of a pool of latently HIV-1-infected cells despite combination Anti-Retroviral Therapy (cART) treatment is the major roadblock for a cure. The BAF (mammalian SWI/SNF) chromatin remodeling complex is involved in establishing and maintaining viral latency, making it an attractive drug...

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書誌詳細
出版年:Cell Chem Biol
主要な著者: Marian, Christine A., Stoszko, Mateusz, Wang, Lili, Leighty, Matthew W., de Crignis, Elisa, Maschinot, Chad A., Gatchalian, Jovylyn, Carter, Benjamin C., Chowdhury, Basudev, Hargreaves, Diana C., Duvall, Jeremy R., Crabtree, Gerald R., Mahmoudi, Tokameh, Dykhuizen, Emily C.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404985/
https://ncbi.nlm.nih.gov/pubmed/30197195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.08.004
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