Small Molecule Targeting of Specific BAF (mSWI/SNF) complexes for HIV Latency Reversal

The persistence of a pool of latently HIV-1-infected cells despite combination Anti-Retroviral Therapy (cART) treatment is the major roadblock for a cure. The BAF (mammalian SWI/SNF) chromatin remodeling complex is involved in establishing and maintaining viral latency, making it an attractive drug...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cell Chem Biol
Main Authors: Marian, Christine A., Stoszko, Mateusz, Wang, Lili, Leighty, Matthew W., de Crignis, Elisa, Maschinot, Chad A., Gatchalian, Jovylyn, Carter, Benjamin C., Chowdhury, Basudev, Hargreaves, Diana C., Duvall, Jeremy R., Crabtree, Gerald R., Mahmoudi, Tokameh, Dykhuizen, Emily C.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404985/
https://ncbi.nlm.nih.gov/pubmed/30197195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2018.08.004
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares