लोड हो रहा है...
Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases
Hedgehog (Hh) induces signaling by promoting the reciprocal trafficking of its receptor Patched (Ptc) and the signal transducer Smoothened (Smo), which is inhibited by Ptc, at the cell surface. We identified Smurf family E3 ubiquitin ligases as essential for Smo ubiquitination and cell surface clear...
में बचाया:
| में प्रकाशित: | Sci Signal |
|---|---|
| मुख्य लेखकों: | , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404747/ https://ncbi.nlm.nih.gov/pubmed/29438012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aan8660 |
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