VEGF receptor-1 modulates amyloid β 1-42 oligomer-induced senescence in brain endothelial cells

Aggregated amyloid β (Aβ) peptides in the Alzheimer’s disease (AD) brain are hypothesized to trigger several downstream pathologies, including cerebrovascular dysfunction. Previous studies have shown that Aβ peptides can have antiangiogenic properties, which may contribute to vascular dysfunction in...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Singh Angom, Ramcharan, Wang, Ying, Wang, Enfeng, Pal, Krishnendu, Bhattacharya, Santanu, Watzlawik, Jens O., Rosenberry, Terrone L., Das, Pritam, Mukhopadhyay, Debabrata
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404587/
https://ncbi.nlm.nih.gov/pubmed/30576228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201802003R
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