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NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression
Increasing evidence shows that many transcription factors execute important biologic functions independent from their DNA-binding capacity. The NF-κB p65 (RELA) subunit is a central regulator of innate immunity. Here, we investigated the relative functional contribution of p65 DNA-binding and dimeri...
Shranjeno v:
| izdano v: | FASEB J |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Federation of American Societies for Experimental Biology
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404571/ https://ncbi.nlm.nih.gov/pubmed/30526044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201801638R |
| Oznake: |
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