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Single-Cell Analysis of Multiple Steps of Dynamic NF-κB Regulation in Interleukin-1α-Triggered Tumor Cells Using Proximity Ligation Assays

The frequently occurring heterogeneity of cancer cells and their functional interaction with immune cells in the tumor microenvironment raises the need to study signaling pathways at the single cell level with high precision, sensitivity, and spatial resolution. As aberrant NF-κB activity has been i...

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Publicat a:Cancers (Basel)
Autors principals: Mayr-Buro, Christin, Schlereth, Eva, Beuerlein, Knut, Tenekeci, Ulas, Meier-Soelch, Johanna, Schmitz, M. Lienhard, Kracht, Michael
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721548/
https://ncbi.nlm.nih.gov/pubmed/31426445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081199
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