The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB

Histone deacetylase (HDAC) 3, as a cofactor in co-repressor complexes containing silencing mediator for retinoid or thyroid-hormone receptors (SMRT) and nuclear receptor co-repressor (N-CoR), has been shown to repress gene transcription in a variety of contexts. Here, we reveal a novel role for HDAC...

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Detalhes bibliográficos
Main Authors: Ziesché, Elisabeth, Kettner-Buhrow, Daniela, Weber, Axel, Wittwer, Tobias, Jurida, Liane, Soelch, Johanna, Müller, Helmut, Newel, Doris, Kronich, Petra, Schneider, Heike, Dittrich-Breiholz, Oliver, Bhaskara, Srividya, Hiebert, Scott W., Hottiger, Michael O., Li, Haiying, Burstein, Ezra, Schmitz, M. Lienhard, Kracht, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592411/
https://ncbi.nlm.nih.gov/pubmed/23087373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks916
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