Phosphorylation of NF-κB p65 at Ser468 controls its COMMD1-dependent ubiquitination and target gene-specific proteasomal elimination

The nuclear factor-kappaB (NF-κB) transcription factor system is a crucial component that controls several important biological functions, thus raising the need for mechanisms that ensure the correct termination of its activity. Here, we identify a new phosphorylation/ubiquitination switch in the NF...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Geng, Hui, Wittwer, Tobias, Dittrich-Breiholz, Oliver, Kracht, Michael, Schmitz, Michael Lienhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672889/
https://ncbi.nlm.nih.gov/pubmed/19270718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.10
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados