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Small Molecule Inhibitors of the PCSK9·LDLR Interaction

The protein–protein interaction between proprotein convertase subtilisin/kexin type 9 (PCSK9) and low-density lipoprotein receptor (LDLR) is a relatively new, and extremely important, validated therapeutic target for treatment and prevention of heart disease. Experts in the area agree that the first...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Taechalertpaisarn, Jaru, Zhao, Bosheng, Liang, Xiaowen, Burgess, Kevin
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404525/
https://ncbi.nlm.nih.gov/pubmed/29378408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09360
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