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Small Molecule Inhibitors of the PCSK9·LDLR Interaction
The protein–protein interaction between proprotein convertase subtilisin/kexin type 9 (PCSK9) and low-density lipoprotein receptor (LDLR) is a relatively new, and extremely important, validated therapeutic target for treatment and prevention of heart disease. Experts in the area agree that the first...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404525/ https://ncbi.nlm.nih.gov/pubmed/29378408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09360 |
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