Structure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding events

Hsp104 is an AAA+ protein disaggregase with powerful amyloid-remodeling activity. All nonmetazoan eukaryotes express Hsp104 while eubacteria express an Hsp104 ortholog, ClpB. However, most studies have focused on Hsp104 from Saccharomyces cerevisiae and ClpB orthologs from two eubacterial species. T...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Structure
Egile Nagusiak: Michalska, Karolina, Zhang, Kaiming, March, Zachary M., Hatzos-Skintges, Catherine, Pintilie, Grigore, Bigelow, Lance, Castellano, Laura M., Miles, Leann J., Jackrel, Meredith E., Chuang, Edward, Jedrzejczak, Robert, Shorter, James, Chiu, Wah, Joachimiak, Andrzej
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6403000/
https://ncbi.nlm.nih.gov/pubmed/30595457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.11.001
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