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Homologous recombination and the formation of complex genomic rearrangements
The maintenance of genome integrity involves multiple independent DNA damage avoidance and repair mechanisms. Yet, the origin and pathways of the focal chromosomal reshuffling phenomena collectively referred to as chromothripsis remain mechanistically obscure. Here, we discuss the role, mechanisms,...
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| Pubblicato in: | Trends Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402879/ https://ncbi.nlm.nih.gov/pubmed/30497856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.10.006 |
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