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Homologous recombination and the formation of complex genomic rearrangements
The maintenance of genome integrity involves multiple independent DNA damage avoidance and repair mechanisms. Yet, the origin and pathways of the focal chromosomal reshuffling phenomena collectively referred to as chromothripsis remain mechanistically obscure. Here, we discuss the role, mechanisms,...
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| Publicado no: | Trends Cell Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6402879/ https://ncbi.nlm.nih.gov/pubmed/30497856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.10.006 |
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