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Moving forward one step back at a time: reversibility during homologous recombination

DNA double-strand breaks are genotoxic lesions whose repair can be templated off an intact DNA duplex through the conserved homologous recombination (HR) pathway. Because it mainly consists of a succession of non-covalent associations of molecules, HR is intrinsically reversible. Reversibility serve...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Piazza, Aurèle, Heyer, Wolf-Dietrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027933/
https://ncbi.nlm.nih.gov/pubmed/31123771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-019-00995-7
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