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A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination

A mild and practical method for the catalytic installation of the amino group across alkenes and alkynes has long been recognized as a significant challenge in synthetic chemistry. As the direct hydroamination of olefins using ammonia requires harsh conditions, the development of suitable electrophi...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Guo, Sheng, Yang, Jeffrey C., Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6402768/
https://ncbi.nlm.nih.gov/pubmed/30371077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b10564
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