Nalaganje...
Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis
BACKGROUND: CEACAM1 regulates insulin sensitivity by promoting insulin clearance. Accordingly, global C57BL/6J.Cc1(−/−) null mice display hyperinsulinemia due to impaired insulin clearance at 2 months of age, followed by insulin resistance, steatohepatitis, visceral obesity and leptin resistance at...
Shranjeno v:
| izdano v: | Metabolism |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6401268/ https://ncbi.nlm.nih.gov/pubmed/30664851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2019.01.008 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|