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SAT-151 Hyperinsulinemia-Driven Progressive Metabolic Dysfunction in Male Mice with Liver-Specific CEACAM1 Deletion
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance. Mice with global null mutation (Cc1(-/-)) or with liver-specific inactivation (L-SACC1) of Ceacam1 gene display hyperinsulinemia due to impaired insulin clearance...
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| Publicado no: | J Endocr Soc |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552123/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-151 |
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