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KRAS-mutant colon cancer cells respond to combined treatment of ABT263 and axitinib

Significant challenges to develop selective and effective pharmacological inhibitors for important oncoproteins like RAS continue impeding the success to treat cancers driven by such mutations. In the present study, the ABT263 and axitinib combination imposed synergistic effects on RAS-mutant colon...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Biosci Rep
Päätekijät: Wang, Guihua, Huang, Ying, Wu, Zhipeng, Zhao, Chunmei, Cong, Hui, Ju, Shaoqing, Wang, Xudong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Portland Press Ltd. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400663/
https://ncbi.nlm.nih.gov/pubmed/30674639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181786
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