GLP-1 signaling suppresses menin’s transcriptional block by phosphorylation in β cells

Both menin and glucagon-like peptide 1 (GLP-1) pathways play central yet opposing role in regulating β cell function, with menin suppressing, and GLP-1 promoting, β cell function. However, little is known as to whether or how GLP-1 pathway represses menin function. Here, we show that GLP-1 signaling...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Xing, Bowen, Ma, Jian, Jiang, Zongzhe, Feng, Zijie, Ling, Sunbin, Szigety, Katy, Su, Wen, Zhang, Longmei, Jia, Ruirui, Sun, Yanmei, Zhang, Lin, Kong, Xiangchen, Ma, Xiaosong, Hua, Xianxin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2019
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6400573/
https://ncbi.nlm.nih.gov/pubmed/30792230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201805049
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge