Squamosamide Derivative FLZ Protects Pancreatic β-Cells from Glucotoxicity by Stimulating Akt-FOXO1 Pathway

Chronic hyperglycemia increases apoptosis and reduces glucose-stimulated insulin secretion. Although protective agents have been searched extensively, none has been found so far. Here we tested FLZ, a synthetic derivative of squamosamide from a Chinese herb, as a potential candidate for antiglucotox...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Diabetes Res
Päätekijät: Kong, Xiangchen, Zhang, Longmei, Hua, Xianxin, Ma, Xiaosong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488173/
https://ncbi.nlm.nih.gov/pubmed/26167511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/803986
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