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A Radical Intermediate in Bacillus subtilis QueE During Turnover With the Substrate Analog 6-Carboxypterin
7-Carboxy-7-deazaguanine (CDG) synthase (QueE), a member of the radical S-deoxyadenosyl-L-methionine (SAM) superfamily of enzymes, catalyzes a radical-mediated ring rearrangement required to convert 6-carboxy-5,6,7,8-tetrahydropterin (CPH(4)) into CDG, forming the 7-dezapurine precursor to all pyrro...
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| Publicat a: | J Am Chem Soc |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6400276/ https://ncbi.nlm.nih.gov/pubmed/29303575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10860 |
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