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Polygenic Risk Score Analysis of Alzheimer’s Disease in Cases without APOE4 or APOE2 Alleles

The We and others have previously shown that polygenic risk score analysis (PRS) has considerable predictive utility for identifying those at high risk of developing Alzheimer’s disease (AD) with an area under the curve (AUC) of >0.8. However, by far the greatest determinant of this risk is the a...

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Detalhes bibliográficos
Publicado no:J Prev Alzheimers Dis
Main Authors: Escott-Price, V., Myers, A., Huentelman, M., Shoai, M., Hardy, John
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399990/
https://ncbi.nlm.nih.gov/pubmed/30569081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14283/jpad.2018.46
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