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Polygenic Risk Score Analysis of Alzheimer’s Disease in Cases without APOE4 or APOE2 Alleles

The We and others have previously shown that polygenic risk score analysis (PRS) has considerable predictive utility for identifying those at high risk of developing Alzheimer’s disease (AD) with an area under the curve (AUC) of >0.8. However, by far the greatest determinant of this risk is the a...

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Библиографические подробности
Опубликовано в: :J Prev Alzheimers Dis
Главные авторы: Escott-Price, V., Myers, A., Huentelman, M., Shoai, M., Hardy, John
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399990/
https://ncbi.nlm.nih.gov/pubmed/30569081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14283/jpad.2018.46
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