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Structures of an RNA Polymerase Promoter Melting Intermediate Elucidate DNA Unwinding
A key regulated step of transcription in all cellular organisms is promoter melting by the RNA polymerase (RNAP) to form the open promoter complex(1–3). To generate the open complex, the conserved catalytic core of the RNAP combines with initiation factors to locate promoter DNA, unwind 12–14 base p...
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| 出版年: | Nature |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399747/ https://ncbi.nlm.nih.gov/pubmed/30626968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0840-5 |
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