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Structures of an RNA Polymerase Promoter Melting Intermediate Elucidate DNA Unwinding

A key regulated step of transcription in all cellular organisms is promoter melting by the RNA polymerase (RNAP) to form the open promoter complex(1–3). To generate the open complex, the conserved catalytic core of the RNAP combines with initiation factors to locate promoter DNA, unwind 12–14 base p...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Boyaci, Hande, Chen, James, Jansen, Rolf, Darst, Seth A., Campbell, Elizabeth A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399747/
https://ncbi.nlm.nih.gov/pubmed/30626968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0840-5
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