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Reorganisation of an RNA polymerase–promoter DNA complex for DNA melting

Sigma factors, the key regulatory components of the bacterial RNA polymerase (RNAP), direct promoter DNA binding and DNA melting. The σ(54)-RNAP forms promoter complexes in which DNA melting is only triggered by an activator and ATP hydrolysis-driven reorganisation of an initial σ(54)-RNAP–promoter...

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Autors principals: Burrows, Patricia C, Severinov, Konstantin, Buck, Martin, Wigneshweraraj, Siva R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC524386/
https://ncbi.nlm.nih.gov/pubmed/15470504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600406
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