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Reorganisation of an RNA polymerase–promoter DNA complex for DNA melting

Sigma factors, the key regulatory components of the bacterial RNA polymerase (RNAP), direct promoter DNA binding and DNA melting. The σ(54)-RNAP forms promoter complexes in which DNA melting is only triggered by an activator and ATP hydrolysis-driven reorganisation of an initial σ(54)-RNAP–promoter...

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Autori principali: Burrows, Patricia C, Severinov, Konstantin, Buck, Martin, Wigneshweraraj, Siva R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC524386/
https://ncbi.nlm.nih.gov/pubmed/15470504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600406
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