Lysophosphatidic acid type 2 receptor agonists in targeted drug development offer broad therapeutic potential

The growth factor-like lipid mediator, lysophosphatidic acid (LPA), is a potent signaling molecule that influences numerous physiologic and pathologic processes. Manipulation of LPA signaling is of growing pharmacotherapeutic interest, especially because LPA resembles compounds with drug-like featur...

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Tigyi, Gabor J., Johnson, Leonard R., Lee, Sue Chin, Norman, Derek D., Szabo, Erzsebet, Balogh, Andrea, Thompson, Karin, Boler, Alyssa, McCool, W. Shannon
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
JLR Perspectives
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399510/
https://ncbi.nlm.nih.gov/pubmed/30692142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.S091744
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