The LPA(2) receptor agonist Radioprotectin-1 spares Lgr5-positive intestinal stem cells from radiation injury in murine enteroids

Rapidly proliferating cells are highly sensitive to ionizing radiation and can undergo apoptosis if the oxidative and genotoxic injury exceed the defensive and regenerative capacity of the cell. Our earlier work has established the antiapoptotic action of the growth factor-like lipid mediator lysoph...

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Bibliografiske detaljer
Udgivet i:Cell Signal
Main Authors: Kuo, Bryan, Szabó, Erzsébet, Lee, Sue Chin, Balogh, Andrea, Norman, Derek, Inoue, Asuka, Ono, Yuki, Aoki, Junken, Tigyi, Gábor
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163127/
https://ncbi.nlm.nih.gov/pubmed/30063964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2018.07.007
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